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布帕尼西鹽酸鹽Buparlisib Hydrochloride (BKM120 Hydrochloride) 是一種 pan-class I PI3K 抑制劑，作用于p110α/p110β/p110δ/p110γ，IC50 分別為 52 nM/166 nM/116 nM/262 nM。
中文別名:
BKM120(鹽酸鹽)
[1]. Burger MT, et al. Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer. ACS Med Chem Lett. 2011 Aug 26;2(10):774-9.
[2]. Zheng Y, et al. Novel phosphatidylinositol 3-kinase inhibitor NVP-BKM120 induces apoptosis in myeloma cells and shows synergistic anti-myeloma activity with dexamethasone. J Mol Med (Berl). 2012 Jun;90(6):695-706.
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